Is gleason score in transrectal ultrasound guided prostate biopsy consistent with gleason score in radical prostatectomy?
Kuwait Medical Journal, cilt.53, sa.2, ss.145-149, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 53 Sayı: 2
- Basım Tarihi: 2021
- Dergi Adı: Kuwait Medical Journal
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
- Sayfa Sayıları: ss.145-149
- Anahtar Kelimeler: Gleason score, radical prostatectomy, transrectal ultrasonography guided prostate biopsy
- Uşak Üniversitesi Adresli: Evet
Özet
Objective: To search for the consistency of Gleason scores (GS) between patients with radical prostatectomy (RP) and with transrectal ultrasonography-guided prostate biopsy (TRUS-Bx) Design: Retrospective study Setting: Urology Clinic of Tepecik Health Research and Application Center of the University of Health Science Subjects: A total of 418 patients diagnosed with prostate cancer following TRUS-Bx and who underwent subsequent RP between 2007 and 2014 were included in the study. Intervention: All patients’ ages, prostate specific antigen values before TRUS-Bx, prostate volumes, biopsy GS, number of positive cores in TRUS-Bx, highest percentage of cancer in a biopsy core, RP specimen GS and risk class by D’Amico risk classification were recorded. Main outcome measures: The compatibility of GS was investigated using prostatectomy and biopsy specimens. Results: GS of biopsy and RP specimens were compatible in 282 (67.5%) patients but incompatible in 136 (32.5%) patients. Of the 136 patients having discordant values of GS, higher GS were determined in 97 (23.2%) whereas lower GS were detected in 39 (9.3%) patients at the end of RP. The sensitivity rates for having low, moderate and high risk after TRUS-Bx were 93.7%, 72.3% and 74.1%, respectively, which was statistically significant in the low risk group (P <.001) Conclusion: In two-thirds of patients, biopsy GS was consistent with RP specimen GS.