The mean platelet volume and atherogenic index of plasma in nondipper normotensive individuals compared to dippers
Clinical and Experimental Hypertension, vol.35, no.1, pp.35-39, 2013 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 35 Issue: 1
- Publication Date: 2013
- Doi Number: 10.3109/10641963.2012.689043
- Journal Name: Clinical and Experimental Hypertension
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.35-39
- Keywords: Atherogenic index of plasma, Dippers, Mean platelet volume, Nondippers, Normotensive
- Uşak University Affiliated: No
Abstract
Mean platelet volume (MPV) is a determinant of platelet activation. Atherogenic index of plasma (AIP), which is defined as the logarithm of the ratio of plasma level of triglycerides to the level of high-density lipoprotein (HDL)-cholesterol (log[TG/HDL-C]), has recently been used as a marker of atherogenicity. This study included 104 normotensive individuals. Mean platelet volume and AIP were measured in all patients. Nondipper individuals (8.6 ± 0.9 fL, 0.3 ± 0.2) demonstrated higher values of MPV and AIP compared with dippers (7.9 ± 1.1 fL, 0.1 ± 0.2) (P < .001 and < .001, respectively). Mean platelet volume and AIP have a positive correlation with insufficient decline in nocturnal blood pressure. © 2013 Informa Healthcare USA, Inc.