The mean platelet volume and atherogenic index of plasma in nondipper normotensive individuals compared to dippers

Yildiz G., HÜR E., ÖZÇİÇEK A., CANDAN F., Kayatas M.

Clinical and Experimental Hypertension, vol.35, no.1, pp.35-39, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 1
  • Publication Date: 2013
  • Doi Number: 10.3109/10641963.2012.689043
  • Journal Name: Clinical and Experimental Hypertension
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.35-39
  • Keywords: Atherogenic index of plasma, Dippers, Mean platelet volume, Nondippers, Normotensive
  • Uşak University Affiliated: No

Abstract

Mean platelet volume (MPV) is a determinant of platelet activation. Atherogenic index of plasma (AIP), which is defined as the logarithm of the ratio of plasma level of triglycerides to the level of high-density lipoprotein (HDL)-cholesterol (log[TG/HDL-C]), has recently been used as a marker of atherogenicity. This study included 104 normotensive individuals. Mean platelet volume and AIP were measured in all patients. Nondipper individuals (8.6 ± 0.9 fL, 0.3 ± 0.2) demonstrated higher values of MPV and AIP compared with dippers (7.9 ± 1.1 fL, 0.1 ± 0.2) (P < .001 and < .001, respectively). Mean platelet volume and AIP have a positive correlation with insufficient decline in nocturnal blood pressure. © 2013 Informa Healthcare USA, Inc.