The relationship between magnesium levels and mortality in the respiratory intensive care unit


Cirik M. Ö., Kilinç M., Doǧanay G. E., Ünver M., Yildiz M., Avci S.

Medicine (United States), vol.99, no.52, 2020 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 99 Issue: 52
  • Publication Date: 2020
  • Doi Number: 10.1097/md.0000000000023290
  • Journal Name: Medicine (United States)
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database, Directory of Open Access Journals
  • Keywords: Acute respiratory failure, Hypermagnesemia, Intensive care unit, Magnesium level, Mortality
  • Uşak University Affiliated: Yes

Abstract

Magnesium deficiency is defined as a pathophysiologic factor in numerous illnesses. This study aims to define the effects of magnesium levels onpatients in the intensive care unit (ICU) regarding length of stay in the ICU, lengthofmechanical ventilation (MV), and 28-daymortality. The following data were collected during initial assessment of patients admitted to the ICU with acute respiratory failure (ARF). Demographic data, magnesium and potassium levels, Charlson's Comorbidity Index (CCI), Acute Physiology and Chronic Health Evaluation (APACHE) II and Sequential Organ Failure Assessment (SOFA) scores, length of MV, length of hospital stay in the ICU, 28- day mortality, and ICU discharge status. In the initial serum analysis prior to treatment of patients in the ICU, the mortality rate of the patient group with hypermagnesemia was found to be statistically significant when compared with other magnesium levels (P=.018). Apart from renal failure, ICU mortality is higher in the hypermagnesemia group than other groups. Hypermagnesemia is an electrolyte abnormality that is generally seen in older individuals and those with serious comorbidity and it can be used in mortality prediction. Abbreviations: ICU = intensive care unit, MV = mechanical ventilation, ARF = acute respiratory failure, CCI = Charlson's Comorbidity Index, APACHE II = Acute Physiology and Chronic Health Evaluation, SOFA = Sequential Organ Failure Assessment, COPD = Chronic obstructive pulmonary disease.