Antimicrobial activity of an endemic species, Thermopsis turcica, Turkey

Korcan S. E., Ciǧerci I. H., Dilek M., Kargioǧlu M., Cenkcil S., Konuk M.

Kuwait Journal of Science and Engineering, vol.36, no.1 A, pp.101-112, 2009 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 1 A
  • Publication Date: 2009
  • Journal Name: Kuwait Journal of Science and Engineering
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.101-112
  • Keywords: Antimicrobial activity, Endangered-endemic, Fabaceae, Thermopsis turcica, Turkey
  • Uşak University Affiliated: No

Abstract

Thermopsis turcica (Kit et al. 1983) is a medicinal wild growing plant endemic to Turkey. In this study, successive extracts of leaf, rhizome stem and callus extracts with n-hexane, ethyl acetate, methanol and diethyl ether were tested for antimicrobial activity against 8 strains of bacteria and 1 strain of fungus using disk diffusion and bioautography assays. As methanol extractions produced the highest crude extracts, alkaloids are the main metabolites of T. turcica. The results from the disc diffusion method showed that 100 μg/ml callus extracts of n-hexane, methanol and diethyl ether inhibited the growth of all tested microorganisms. In the bioautography assay, methanol extracts of rhizome stem and leaves produced the highest inhibition zones against. These results indicated that this endangered species has strong antimicrobial compounds against human pathogenic microorganisms, stressing the need for further investigations using fractionated extracts and purified chemical components.