Indian Journal of Surgery, 2022 (SCI-Expanded)
Primary hyperparathyroidism is a result of overproduction of parathyroid hormone by parathyroid adenoma. Surgical indication of primary hyperparathyroidism is well defined; however, nonspecific symptoms and their effect on quality of patients’ life are not considered on surgical decision-making. The aim of this study is to evaluate the effect of surgical therapy for primary hyperparathyroidism on general and swallowing related quality of life. This cohort study was conducted prospectively between November 2018 and July 2020. There were 145 patients with primary hyperparathyroidism included in data analysis. Patient operated for primary hyperparathyroidism were included in the study. General health–related and swallowing-related quality of life was evaluated before and after the surgery. Improvement of general health–related quality of life was detected in 7 out of 8 domains of short form 36 questionnaire. Improvement of eating-related quality of life was detected in all domains of swallowing-related quality of life questionnaire. Nonspecific or neuropsychiatric symptoms of PHPT should be evaluated before decision-making for the treatment and should be considered in surgical indications for PHPT.