Impact of geriatric nutritional index in contrast-induced nephropathy developed in patients with non-st segment elevation myocardial infarction who underwent percutaneous coronary intervention Geriyatrik beslenme indeksinin perkütan koroner girişim uygulanmış st segment yükselmesiz miyokard infarktüslü hastalarda gelişen kontrast kaynaklı nefropati üzerine olan etkisi

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Kucukosmanoglu M., Yildirim A., Yavuz F., Dogdus M., Kilic S.

Medeniyet Medical Journal, vol.35, no.1, pp.47-54, 2020 (Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.5222/mmj.2020.86094
  • Journal Name: Medeniyet Medical Journal
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.47-54
  • Keywords: Contrast induced nephropathy, Geriatric nutritional index, Percutaneous coronary intervention
  • Uşak University Affiliated: Yes

Abstract

Objective: Geriatric nutritional risk index (GNRI) is a useful tool to determine the nutritional status of pa-tients. Any study has not evaluated the impact of GNRI in development of contrast-induced nephropathy (CIN) after percutaneous coronary intervention (PCI). We aimed to evaluate whether GNRI could predict CIN after PCI. Method: A total of 1116 patients with non-ST elevation myocardial infarction (non-STEMI) that underwent PCI were enrolled to the present study. The GNRI was calculated using a previously reported formula: GNRI=14.89 × albumin (g/dL) + 41.7 × body weight (kg)/ideal body weight (kg). CIN was defined as an increase in serum creatinine level of ≥0.5 mg/dL or ≥25% above baseline within 72 hours after the PCI procedure. The patients were categorized into two groups as CIN (+) and CIN (-). Results: The mean age of the CIN (+) group was significantly higher than the CIN (–) group (64.8±10.67 vs. 60.5±10.61 years; p<0.001). The mean values of height, weight, and body mass index were significanlty lower in CIN (+) group than CIN (-) group (p<0.001, for all). The mean of GNRI was significantly lower in the CIN (+) group than the CIN (-) group (101.4±8.7 vs. 112.1±12.9; p<0.001). Serum albumin level was significantly lower in the CIN (+) group (3.71±0.52 g/dL vs. 3.94±0.53 g/dL; p<0.001). Left ventricular ejec-tion fraction (LVEF) was significantly lower in the CIN (+) group (50.7%±9.07 vs. 54.3%±7.20; p<0.001). Conclusion: In this study, GNRI, serum albumin level, BMI, and LVEF were independent predictors of CIN. Moreover, GNRI was better than both serum albumin level and BMI in predicting development of CIN.