Factors determining biochemical recurrence in low-risk prostate cancer patients who underwent radical prostatectomy
Turk Uroloji Dergisi, cilt.41, sa.2, ss.61-66, 2015 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 41 Sayı: 2
- Basım Tarihi: 2015
- Doi Numarası: 10.5152/tud.2015.65624
- Dergi Adı: Turk Uroloji Dergisi
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.61-66
- Anahtar Kelimeler: Biochemical recurrence, low-risk, radical prostatectomy
- Uşak Üniversitesi Adresli: Evet
Özet
Objective: This study was conducted to research the factors determining biochemical recurrence (BCR) in low-risk localized prostate cancer patients who underwent radical prostatectomy (RP). Material and methods: We retrospectively analyzed the data of 504 patients who had undergone RP between 2003 and 2013 at our clinic. One hundred and fifty-two patients who underwent RP for low-risk prostate cancer were included in the study. Results: The mean follow-up period for patients was 58.7 (21–229) months. The mean age of the patients was 63.7±7.2 years (49–79). The mean prostate specific antigen (PSA) value was 5.25±4.22 ng/mL (3.58– 9.45). The BCR rate after the operation was 25% (38/152). In the univariate analysis, recurrence determining factors were shown to include extracapsular involvement (ECI) (p=0.004), capsular invasion (CI) (p=0.001), age (p=0.014), and tumor size (p=0.006). However, only CI was found to be significant in multivariate analysis (p=0.001). Conclusion: Capsular invasion is an independent risk factor in low-risk prostate cancer patients who underwent RP for BCR.