Akademik Veri Yönetim Sistemi
Perspectives in Psychiatric Care, cilt.2026, sa.1, 2026 (SCI-Expanded, SSCI, Scopus)
Aim: To investigate potential factors that might influence the achievement of the minimum clinically important difference (MCID) in walking fitness following cardiac rehabilitation (CR) in patients with and without new-onset depression. Methods: The clinical data from the National Audit of CR (NACR) indicated that between January 1, 2016, and January 31, 2020, 2027 acute coronary syndrome (ACS) patients with new-onset depression (15.5%) and 11,059 without new-onset depression (84.5%) underwent pre- and postincremental shuttle walk test (ISWT) measurements. Patients with new-onset depression had a mean age of 61.7 ± 10.5 years (27.5% female), compared to 64.8 ± 10.3 years (20.6% female) among those without. Comparative analyses were conducted to examine differences in walking fitness between these groups. Subsequently, a binary logistic regression analysis was executed to investigate the factors associated with achieving the MCID in walking fitness, defined as > 70 m improvement in ISWT, following CR. Results: The multivariate analysis results revealed that having new-onset depression (OR: 0.89, 95% CI: 0.80 and 0.99), older age (OR: 0.96, 95% CI: 0.95 and 0.96), female gender (OR: 0.61, 95% CI: 0.56 and 0.68), physical inactivity (OR: 0.84, 95% CI: 0.78 and 0.91), and obesity (OR: 0.65, 95% CI: 0.60 and 0.71) were all associated with being less likely to achieve MCID in walking fitness adjusting for baseline fitness levels. Patients with new-onset depression had reduced walking fitness at baseline compared to those without, and they were less likely to meet the MCID for ISWT following CR. The study also generated a novel set of walking fitness reference values for patients with new-onset depression.