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Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi, vol.12, no.1, pp.61-66, 2025 (Peer-Reviewed Journal)
Immunodeficiency refers to deficiencies or dysfunctions in the components of the immune system and the associated clinical manifestations. The conditions leading to immunodeficiency are highly heterogeneous and are primarily classified into primary and secondary immunodeficiencies. Acute otitis media is one of the most common infections in children with a normal immune system. However, the frequent occurrence of otitis media in children without immunodeficiency can complicate the diagnosis of immunodeficiency in affected children. Managing recurrent and severe infections in the pediatric population poses significant challenges. In a child with otitis media, certain indicative symptoms may suggest an underlying immunological deficiency. In this review, the middle ear diseases observed in children with immunodeficiency, as well as their management and treatments, are discussed.