The assessment of P-wave dispersion and myocardial repolarization parameters in patients with chronic kidney disease

Kollu K., Altintepe L., DURAN C., Topal M., Ecirli S.

Renal Failure, cilt.40, sa.1, ss.1-7, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1080/0886022x.2017.1419962
  • Dergi Adı: Renal Failure
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1-7
  • Anahtar Kelimeler: P-wave dispersion; QTc dispersion; Tp-e dispersion; Tp-e/QT ratio; chronic kidney disease; arrhytmias
  • Uşak Üniversitesi Adresli: Evet

Özet

Objective: The risks of sudden death and cardiac arrhythmia are increased in patients with chronic kidney disease (CKD). Here, we aimed to evaluate the indicators of arrhythmias, such as p-wave dispersion (P-WD), QTc dispersion, Tp-e and Tp-e/QT ratio in patients with CKD stages 3–5 on no renal replacement therapy (RRT). Material and methods: One-hundred and thirty three patients with CKD stages 3–5 and 32 healthy controls were enrolled into the study. No patients received RRT. QTc dispersion, P-WD and Tp-e interval were measured using electrocardiogram and Tp-e/QT ratio was also calculated. Results: Mean age rates were found similar in patients and controls (60.8 ± 14.2 and 61 ± 12.9 y, p =.937, respectively). Compared patients with controls, P-WD (45.85 ± 12.42 vs. 21.17 ± 6.6 msec, p <.001), QTc-min (366.99 ± 42.31 vs. 387.15 ± 20.5 msec, p <.001), QTc dispersion (71.13 ± 27.95 vs. 41.25 ± 14.55 msec, p <.001), Tp-e maximum (81.04 ± 10.34 vs. 75.49 ± 10.9 msec, p <.001), Tp-e minimum (62.25 ± 7.58 vs. 54.8 ± 6.72 msec, p <.001) and Tp-e/QTc ratio (0.19 ± 0.02 vs. 0.18 ± 0.01, p =.001) were found to be different. QTc-max and Tp-e interval were found to be similar in both groups. Conclusion: P-WD and QTc dispersion, Tp-e interval and Tp-e/QTc ratio were found to be increased in with CKD stages 3–5 on no RRT.