Acta Medica Mediterranea, cilt.36, sa.2, ss.813-819, 2020 (SCI-Expanded)
Introduction: Obesity and dyslipidemia are important risk factors for atherosclerosis. In this study, we aimed at comparing visceral adiposity index (VAI) levels calculated through anthropometric measurement and lipid levels with atherogenic index of plasma (AIP) levels calculated with only lipid levels in overweight and obese subjects. Materials and methods: Between 18-65 years, 157 obese patients were included. Homeostasis model assessment of insulin resistance (HOMA-IR), VAI and AIP levels were calculated. Results: The study was performed in 105 patients (91 women and 14 men). Regarding AIP risk levels, 9.5% (n=10) of patients were found as low-risk, 2.9% (n=3) as medium and 87.6% (n=92) as high. In high-risk group, HOMA-IR (p=0.026) and VAI (p<0.001) were found higher. VAI and AIP levels were higher among those with body mass index (BMI) (≥35 kg/m2) than those with BMI (25- 29.9 kg/m2) (p=0.009 and p=0.009, respectively). A positive correlation was detected between AIP, and HOMA-IR and VAI. Each 1-cm increase in waist circumference and each one-unit increase in body mass index (BMI) led to increases of 0.009 and 0.028 in AIP, respectively. Conclusions: As the indicators of atherosclerotic CVDs, as VAI and AIP increased, the severity of obesity increased in patients with obesity. There was a positive association between VAI and AIP, and those in high-risk group for AIP had higher VAI levels than those in low-risk group. Thanks to their easy calculation with the formula, VAI and AIP could be used to determine the atherosclerotic risk in such patients.