Akademik Veri Yönetim Sistemi
Clay Minerals, 2024 (SCI-Expanded)
The antibacterial, antifungal, and antioxidant effects of halloysite nanoclay, Cloisite 10A (C10A), and Cloisite 15A (C15A) organonanoclays were examined in this study. The antimicrobial action was assessed using the agar-well method and the disc diffusion method. The free radical scavenging effect of the clays was determined by the 2,2-Diphenyl-1-picrylhydrazyl (DPPH) method. Halloysite showed antimicrobial activity against Pseudomonas aeruginosa, Enterococcus faecalis and Staphylococcus aureus. C10A was effective against both gram-positive bacteria (Staphylococcus aureus, Listeria monocytogenes, Bacillus subtilis, and Enterococcus faecalis) and gram-negative bacteria (Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa). Additionally, only C10A was found to have an antimicrobial effect on Candida glabrata by 18 mm among the tested clays. C15A showed antimicrobial effect on Staphylococcus aureus and Klebsiella pneumoniae. It was determined that the antifungal properties of organoclays were higher than halloysite. The most effective clay type was determined to be C10A. Positively charged inner surface of halloysite nanoclay can provide a large area for the negatively charged free radicals to attach.The modified C15A used in this study has two long chain alkyl groups attached, while the modified C10A has a single long-chain alkyl group and a benzyl group attached. It can be said that the differences in the antimicrobial effect are due to these structures of the molecules. According to these results, organoclays as green source materials are used as additives and coatings in food processing, biomedical devices, filters and paints due to their antimicrobial and antioxidant properties.