Akademik Veri Yönetim Sistemi
Journal of Experimental and Clinical Medicine (Turkey), cilt.34, sa.2, ss.93-97, 2017 (Scopus, TRDizin)
Beta thalassemias are the most common autosomal recessive disorders characterized by anomalies in the synthesis of the beta chains of hemoglobin and are often associated with varying degrees of growth and developmental retardation. In this study, we determined the body fat mass (FM), fat-free mass (FFM), muscle mass (MM), total body water (TBW), extracellular water (ECW), intracellular water (ICW) and body mass index (BMI) by bioelectrical impedance analysis (BIA) in thalassaemia major patients. The body composition and growth conditions of thalassaemia major patients were assessed. A total of 43 patients (22 women and 21 men) with thalassaemia major age of 4-36 years and 26 age- and sex-matched healthy control subjects were included in the study. Height and weight measurements were performed by SECA (Model 767; Germany) and BIA measurements were made by In Body 720. Differences in the height, weight, waist circumference, FFM, MM, TBW, and ICW parameters were also significant (p<0.05). No significance in the abdominal circumference, chest circumference, BMI, FM and ECW parameters (p>0.05) were noted. Our study indicated that body composition is different in thalassaemia major patients when compared with healthy subjects. Bioelectrical impedance analysis is an easy, non-invasive, relatively inexpensive, safe, reproducible and effective evaluation method of the body composition that can be conducted in clinics.